Trends in Pharmaceutical Research and Development Vol. 5

Authors

Dr. M. V. N. L. Chaitanya, (Editor)

Assistant Professor, Dilla University, College of Health Sciences, Pharmacy (Pharmacognosy) Dilla, Ethiopia.

Akanni E. Olufemi

Haematology Division, Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Olaniran O. Isiaka

Department of Pharmacology and Therapeutics, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Akinbo B. David

Haematology Division, Department of Medical Laboratory Science, College of Medicine and Health Sciences, Afe Babalola University, P.M.B. 5454, Ado - Ekiti, Ekiti State, Nigeria.

Iyiola O. Abdulmajid

Haematology Division, Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Ogunlade A. Adebola

Haematology Division, Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Sanni O. Bilikis

Haematology Division, Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Adejumo M. Temitope

Haematology Division, Department of Medical Laboratory Science, College of Health Sciences, Ladoke Akintola University of Technology, P.M.B. 4400, Osogbo, Osun State, Nigeria.

Maira Huerta- Reyes

Unidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades “Dr. Bernardo Sepúlveda Gutiérrez”, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Avenida Cuauhtémoc No. 330, Col. Doctores, 06720, Ciudad de México, México and Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Argentina No. 1, Col. Centro, 62790, Xochitepec, Morelos, México.

Arturo Aguilar-Rojas

Unidad de Investigación Médica en Medicina Reproductiva, Unidad Médica de Alta Especialidad (UMAE) en Ginecología y Obstetricia No. 4 “Dr. Luis Castelazo Ayala”, Instituto Mexicano del Seguro Social, Av. Río Magdalena No. 289, Col. Tizapán San Ángel, 01090, México D.F., México.

Swetal Patel

C. G. Bhakta Institute of Biotechnology1, Uka Tarsadia University, Mahuva Road, Bardoli, Surat (District), Gujarat State, Pin Code: 394350, India.

Nikita Patel

C. G. Bhakta Institute of Biotechnology1, Uka Tarsadia University, Mahuva Road, Bardoli, Surat (District), Gujarat State, Pin Code: 394350, India.

A. A. Abdul Rahaman

Department of Plant Biology, Faculty of Life Sciences, University of Ilorin, Kwara State, Nigeria.

R. Krishnamurthy

C. G. Bhakta Institute of Biotechnology1, Uka Tarsadia University, Mahuva Road, Bardoli, Surat (District), Gujarat State, Pin Code: 394350, India.

María Lourdes Puig San Andrés

Carrera de Especialización en Biotecnología Bioquímico Farmacéutica, Facultad de Farmacia y Bioquímica, de la Universidad de Buenos Aires, Argentina.

Adriana Carlucci

Departamento de Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica, de la Universidad de Buenos Aires, Argentina and Departamento de Farmacia, Instituto Universitario del Hospital Italiano de Buenos Aires, Argentina.

Lucrecia María Curto

Instituto de Química y Fisicoquímica Biológicas (UBA-CONICET), Facultad de Farmacia y Bioquímica, de la Universidad de Buenos Aires, Argentina.

S. Patil

Department of Panchakarma, Dr. Rajendra Gode Ayurved College, Amravati, Maharashtra, India.

A. B. Thakar

Department of Panchakarma, I.P.G.T. & R.A.GAU, Jamnagar, India.

C. R. Harisha

Department of Parmacognocy, I.P.G.T. & R.A.GAU, Jamnagar, India.

V. J. Shukla

Department of Pharmacutical Chemestry, I.P.G.T. & R.A.GAU, Jamnagar, India.

Masheer Ahmed Khan

School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore, 452001, India.

S. C. Chaturvedi

School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore, 452001, India.

Klitsunova Yuliia Aleksandrovna

Department of Family Medicine with the Courses of Dermatovenereology and Psychiatry, SI “Zaporizhzhya Medical Academy of Post-Graduate Education, Ministry of Health of Ukraine, Ukraine.

Ostapenko Andrii Alekseevich

Department of Laboratory Diagnostics and General Pathology, SI “Zaporizhzhya Medical Academy of Post-Graduate Education, Ministry of Health of Ukraine, Ukraine.

Ivahnenko Nataliia Timofeevna

Department of Family Medicine with the Courses of Dermatovenereology and Psychiatry, SI “Zaporizhzhya Medical Academy of Post-Graduate Education, Ministry of Health of Ukraine, Ukraine.

Kulbachuk Aleksandr Sergeevich

Department of Family Medicine with the Courses of Dermatovenereology and Psychiatry, SI “Zaporizhzhya Medical Academy of Post-Graduate Education, Ministry of Health of Ukraine, Ukraine.

Ivaschuk Viktoriia Aleksandrovna

Department of Family Medicine with the Courses of Dermatovenereology and Psychiatry, SI “Zaporizhzhya Medical Academy of Post-Graduate Education, Ministry of Health of Ukraine, Ukraine.

C. A. Anosike

Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

J. C. Ugwu

Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

P. C. Ojeli

Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

S. C. Abugu

Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

Bijay Kumar Sahoo

IMT Pharmacy College Puri, Sai Vihar, Gopalpur, Puri, 752004, Odisha, India.

Annada Prasad Mohapatra

IMT Pharmacy College Puri, Sai Vihar, Gopalpur, Puri, 752004, Odisha, India.

W. Jessie Suneetha

Krishi Vigyan Kendra, PJTS Agricultural University, Wyra 507165, Khammam Dt., India.

B. Anila Kumari

Post Graduate and Research Centre, Department of Foods and Nutrition, Professor Jayashankar Telangana State Agricultural University, Rajendranagar, Hyderabad – 500 030, India.

Nils Von Hentig

HIVCENTER, Medical Department II, Hospital of the J.W. Goethe University, Frankfurt am Main, Germany.

Aparna A. Saraf

Department of Botany, The Institute of Science, Mumbai, Maharashtra, India.

Aruna C. Samant

Department of Botany, The Institute of Science, Mumbai, Maharashtra, India.

Synopsis

This book covers key areas of Pharmaceutical Research. The contributions by the authors include Kigelia africana, cancer, chemotherapy, leukaemia, chemoprevention, Stem Bark, Fruit and Leaf Extracts, nvention, patent, industrial property, Protection of Inventions, Plant Research, Mucuna pruriens, accessions, L-Dopa, breeding, cultivation, harvesting, Stability, formulation, protein, circular dichroism, Second- Generation Biopharmaceutical Product, Lagenaria vulgaris, Ikshvaku, pharmacognosy, phytochemestry, Hydroxy propyl methy cellulose (HPMC), polymers, swelling, matrices, release rate, Hydrophilic Matrices, 24 h ambulatory blood pressure, blood pressure variability, diabetic nephropathy, glycemic control, glycated hemoglobin, hypertension, Ceiba pentandra, diabetes, liver enzymes, lipid profile, gastric ulcer, indomethacin, Anti-ulcerogenic Effects, Nanotechnology, nanoparticles, solid lipid nanoparticles, nano-emulsion, drug delivery, nanomaterials, Quinoa, gluten-free, germination, glycemic index and glycemic load, New antiretrovirals, HIV-therapy, drug-drug-interactions, Legal highs, synthetic illegal drugs, drug-abuse, drug-drug-interactions, cART, Achyranthes aspera Linn., quantification, oleanolic acid, Thin Layer Chromatography, Oleanolic Acid etc. This book contains various materials suitable for students, researchers and academicians in the field of Pharmaceutical Research.

Chapters

Chapter 1
Anti-inflammatory and Anti-leukaemic Activities of the Kigelia africana Stem Bark, Fruit and Leaf Extracts

Akanni E. Olufemi, Olaniran O. Isiaka, Akinbo B. David, Iyiola O. Abdulmajid, Ogunlade A. Adebola, Sanni O. Bilikis, Adejumo M. Temitope
Chapter 2
An Update of the Situation about the Protection of Inventions Derived from Plant Research in a Megadiverse Country: The Case of Mexico

Maira Huerta- Reyes, Arturo Aguilar-Rojas
Chapter 3
Medicinal Plant Mucuna pruriens: From Farm to Pharma

Swetal Patel, Nikita Patel, A. A. Abdul Rahaman, R. Krishnamurthy
Chapter 4
Accelerated Stability Study in Alternative Formulations of a Second- Generation Biopharmaceutical Product

María Lourdes Puig San Andrés, Adriana Carlucci, Lucrecia María Curto
Chapter 5
Phamacognostical & Phamacutical Evaluation of Ikshvaku Churna [Lagenaria vulgaris (Monila) Standly. Fruit Pulp Powder]

S. Patil, A. B. Thakar, C. R. Harisha, V. J. Shukla
Chapter 6
Swelling and Drug Release Studies from Hydrophilic Matrices Containing Combination of Different Grades of Hydroxyl Propyl Methylcellulose

Masheer Ahmed Khan, S. C. Chaturvedi
Chapter 7
Evaluating the Characteristics of Blood Pressure Variability in Subjects with Chronic Kidney Disease Stage III in Diabetic or Non-diabetic Patients

Klitsunova Yuliia Aleksandrovna, Ostapenko Andrii Alekseevich, Ivahnenko Nataliia Timofeevna, Kulbachuk Aleksandr Sergeevich, Ivaschuk Viktoriia Aleksandrovna
Chapter 8
Investigation on the Anti-ulcerogenic Effects and Anti-oxidative Properties of Ceiba pentandra Leaves on Alloxan-induced Diabetic Rats

C. A. Anosike, J. C. Ugwu, P. C. Ojeli, S. C. Abugu
Chapter 9
An Overview on Nano Drug Delivery: Challenges and Its Safety Issues

Bijay Kumar Sahoo, Annada Prasad Mohapatra
Chapter 10
Glycemic Index Profiling of Raw and Germinated Quinoa (Chenopodium quinoa Willd)

W. Jessie Suneetha, B. Anila Kumari
Chapter 11
Highlighting New Antiretrovirals on the Block: Pharmacological News from CROI 2017

Nils Von Hentig
Chapter 12
Study on Potential Drug Interactions between cART and New Psychoactive Substances

Nils Von Hentig
Chapter 13
Recent Advancements of High-Performance Thin Layer Chromatography Method for Identification and Quantification of Oleanolic Acid in the Roots of Achyranthes aspera Linn.

Aparna A. Saraf, Aruna C. Samant